| Number and movement of population | |
| Indicator | Number |
| Average status of the permanently resident population in 2021 |
228 070 |
| /Regional Capital City of Košice/ | |
| out of which women (%): | 52,2 |
| Born alive | 2 155 |
| per 1 000 inhabitants | 9,45 |
| Deceased | 3 173 |
| per 1 000 inhabitants | 13,9 |
| Dead within 1 year | 11 |
| Natural Increase | |
| (decrease) | -1 018 |
| per 1 000 inhabitants | -4,46 |
| Marriages | 1 028 |
| Divorces | 348 |
| Miscarriages | 301 |
| Immigrants | 2 035 |
| Emmigrants | 2 599 |
| Total increase | |
| (decrease) | -1 582 |
| per 1 000 inhabitants | -6,93 |
| Ethnic structure of population | |
| Nationality | as of 31.12.2021 |
| (Regional Capital City of Košice) | |
| Total | 229 040 |
| Slovak | 191 775 |
| Czech | 1 364 |
| Moravian | 46 |
| Silesian | 4 |
| Hungarian | 5 636 |
| Roma | 4 152 |
| Polish | 139 |
| German | 170 |
| Ruthinian | 1 211 |
| Ukrainian | 882 |
| Russian | 176 |
| Jewish | 64 |
| Greek | 21 |
| Bulgarian | 55 |
| Romanian | 28 |
| Austrian | 9 |
| Vietnamies | 354 |
| Other/Unknown | 22 668 |